Nerd Nite SF #76: Building Tissues, 20K Leagues, and Deep Biases!

Nerd Nite SF #76: Building Tissues, 20K Leagues, and Deep Biases!Wednesday, 9/21/16
Doors at 7 pm, show at 8
Rickshaw Stop, 155 Fell St @ Van Ness
$8, all ages
Tickets here

This Wednesday we’re in for quite a ride! We’ll build up the evening with self-organizing tissue assembly, then dive deep into the legacy of the 20,000 Leagues Under the Sea attraction, before leveling off with a talk about the neuroscience and evolutionary biology of the endlessly irrational decisions we make. Throughout the night, enjoy refreshing beverages from the Rickshaw Stop bar, beats by DJ Alpha Bravo, books from the SFPL, and bites from Alicia’s Tamales los Mayas. Buckle up, be there, and be square!

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“How Tissues Build Themselves” by Zev Gartner

The human body contains over 10 trillion cells–spanning hundreds of different cell types–that must work together for our bodies to function. But it remains a mystery how these diverse cells coordinate their behaviors. Tissue structure, the composition and arrangement of the cells, helps this coordination by organizing the flow of information between cells. Learn how Zev’s lab at UCSF constructs tissues in a dish using the same strategies that tissues use to build themselves in the body: through the process of self-organization. Someday, these “built” tissues will engineer transplantable organs and help suppress diseases like cancer.

Zev hails from Santa Cruz, California. Although originally trained to build molecules as a chemist, he now focuses on building tissues. When not in the lab, he tries to find time to surf.

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“A Journey Through Liquid Space: Disney’s 20,000 Leagues Under the Sea Ride” by David Shuff

In 1971, Disney unveiled the greatest theme park attraction ever: the 20K ride. For decades it inspired, delighted, and scared the crap out of anyone with half an imagination. In 1994, the ride was temporarily “closed for maintenance,” but that was a LIE. It never sailed again, and the ruins were unceremoniously demolished in 2004. David Shuff has dedicated himself to keeping the memory and magic of 20K alive, despite having ridden it only once, when he was 3. Sharing rare photos, video, and actual crew-member accounts, he will helm a spine-tingling adventure through the rise, fall, and surprising afterlife of the 20K ride–the lost 8th wonder of the world.

David is a well-rounded human being with a healthy dislike of most things Disney. He’s a video creative at AKQA in San Francisco. Beware the plush giant squid behind his couch.

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“I Am Deeply Biased” by Jacob Ward

This late-breaking addition to our line-up will be a preview of a four-part PBS series Jake is hosting, about the neuroscience and evolutionary biology of the endlessly irrational decisions people make about strangers, food, credit cards, presidents, and everything else in modern life.

You’ll remember Jake from his 2013 NNSF talk, but he’s probably a little more famous for having been a science and tech correspondent for Al Jazeera and the editor-in-chief of Popular Science.

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With: Alpha Bravo, who’ll be spinning tunes specially selected to match the presenters’ themes. Follow the setlist on Twitter @djalphabravo.

Food: Delicious meals from Alicia’s Tamales los Mayas.

Plus: The San Francisco Public Library will be on hand to dole out library cards, reading lists, and the hottest branch gossip.

 

Nerd Nite SF #75: “Sleep Studies, Zapping Proteins, and Driverless Cars”

Nerd Nite SF #75: “Sleep Studies, Zapping Proteins, and Driverless Cars”Wednesday, 8/17/16
Doors at 7 pm, show at 8
Rickshaw Stop, 155 Fell St @ Van Ness
$8, all ages
Tickets here

Ah, the brave new world: Commuters make up their sleep deficits snoozing at the wheels of driverless cars on their way to their jobs using lasers! We are living in the future! Come explore it using the finest in, um, 1990s technology: PowerPoint! With vinyl records (1940s) to tickle your eardrums, grilled cheese (invented circa the Jazz Age) to fill your bellies, SFPL book recommendations (to mark the mid-15th century) for homework, and booze (from time immemorial). Be there and be square!

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“F**ked If You Don’t Sleep!” by Matthew Walker

Allow us to ask you a question: Can you recall the last time you woke up without an alarm clock, feeling refreshed, not needing caffeine? If the answer is “no,” you’re screwed, and this talk will describe why.

Matthew eavesdrops on sleeping brains at night and is a professor of neuroscience at UC Berkeley during the day.

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“Microwaving Proteins with X-Ray Lasers and Galloping Horses” by James Fraser

In 1872, Leland Stanford gave photographer Eadweard Muybridge the task of proving that all four of a horse’s hooves are off the ground at the same time during a gallop. Little did he know he’d be setting in motion (ha!) early cinema, with the concomitant improvements in camera shutters and film emulsions. Fast-forward to today and discover the surprising geographic and scientific parallels between the first “movie” and current efforts to make molecular movies of proteins using the world’s first X-ray free electron laser.

James is a professor at UCSF–where his lab studies the structure and dynamics of macromolecules–and consulting professor at SLAC National Lab, as well as an advocate for the beer-and-tacos approach to scientific publishing, wherein work is made immediately accessible to a wide audience via preprints and eventually also peer-reviewed by traditional journals.

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“Driverless Vehicles: Who’s Really in Control?” by Lauren Isaac

Driverless vehicles have the potential to change so much in our society: Boozers will never have to worry about DUIs, Grandma Gertie can get around without people fearing for their lives, and the millennials can do their elliptical workout while commuting! Are we really going to be safer, though? Will they do more harm than good for society? And who is going to make sure we aren’t just overrun with robo-cars? Who’s really in control and what can we do to prepare for this disruptive technology?

Lauren is a transportation enthusiast/nerd who works at WSP|Parsons Brinckerhoff and has spent her career helping government agencies with public transit, bike sharing, ride sharing and now driverless cars.

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With: Alpha Bravo, who’ll be spinning tunes specially selected to match the presenters’ themes. Follow the setlist on Twitter @djalphabravo.

Food: Delicious hot goop between crispy slices of bread, brought to you by the scientist of the sammie, Grilled Cheese Guy.

Plus: The San Francisco Public Library will be on hand to dole out library cards, reading lists, and the hottest branch gossip.

Nerd Nite SF #74: “Game of Thrones Geology, Flute-Making, and Epigenetics”

Nerd Nite SF #74: “Game of Thrones Geology, Flute-Making, and Epigenetics”Wednesday, 7/20/16
Doors at 7pm, show at 8
Rickshaw Stop, 155 Fell St @ Van Ness
$8, all ages
Tickets here

On the 20th day of Quintilis, the Stop of the Rickshaw will unbar its gates and receive throngs of imbibing smarty pants come to worship at its PowerPoint altar. Will you be among the faithful? If so, remove your health-tracking wristband (a doctor will tell us how our “Fitbits” come factory-installed), pipe down (while we’re schooled on our favorite edge-blown aerophone), and “hodor” for your fellow Game of Thrones aficionados (as we traverse fantasy landscapes with a geologist). In other words: Be there and be square!

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“The Geology of Game of Thrones: Real Science in Fantasy” by Miles Traer

From towering peaks to candlelit crypts, vast seas to vertiginous canyons, the worlds of fantasy stories entice and entrance. But just how realistic is that mountain range? Or that river crossing? Or that wall? Yes, THAT Wall? Using what we know from Earth, we can reconstruct the geological history of mythical places, like Game of Thrones’ Westeros. And when we do, we see that the geological forces that shape our world are just as awesome and terrifying as anything beyond The Wall.

Miles is a geologist and educator at Stanford University and creator of the award-winning Generation Anthropocene podcast. He studies landscape evolution on Earth, Mars, and Saturn’s largest moon, Titan. Explore Miles’s research and pop-sci articles at www.milestraer.com.

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“Piping Up: The Secret World of Flute-Making” by Linda Watkins

Ever wonder how flutes are made? Which is correct: flutist or flautist? (Or fluter? Or flutenist?) And how did these metal tubes end up flouting the “wood” part of “woodwind”? Come learn about the history, science, and art of flute-making in America, including the man who started it all and why all the great American flute makers are in Boston. Not to toot our own flute or anything, but the stories will surprise you! This presentation includes a live performance.

Linda is a flute nerd: She’s played it for over 30 years, has a Masters in Music Performance from Arizona State University, and worked for four years at a flute manufacturing company. Though now in marketing at a startup, she performs regularly with community orchestras and chamber groups.

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“Epigenetic Fitbits: How Genes Can Keep Track of Your Body Weight” by Dr. Lucia Aronica

Our genes are smarter than wearables when it comes to tracking health data. Biological “Fitbits” within our DNA — epigenetic modifications — store information about our lifestyle habits, such as diet, exercise, and stress. But how do these modifications work? How do they track our weight? And how might they help us know which diet works best for us?

Lucia is a research associate at Stanford University and an award-winning science communicator (Ed: Including winner of the 2009 FameLab Germany competition, and third in the final FameLab International competition. Shout-out to the Rickshaw Stop for hosting FameLab heats the past two years in SF, too!).

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With: Alpha Bravo, who’ll be spinning tunes specially selected to match the presenters’ themes. Follow the setlist on Twitter @djalphabravo.

Food: Delicious pork belly-bao and other bun goodness from Cross Hatch Eatery.

Plus: The San Francisco Public Library will be on hand to dole out library cards, reading lists, and the hottest branch gossip.

Nerd Nite SF #73: Mudlarking, Strandbeest Machines, and Mite Sex!

NN-Jun-2016-h700This month’s amusing and occasionally immodest show promises mud, machines, and mites. So put on your tallest boots to walk along the Thames, accompanied by walking PVC construct companions, and perhaps arachnids walking on your skin! Fortify yourself with drinks while our presenters take us on this journey, along with our bartenders, deejay, librarians, and food-slingers. Be there and be square!

Wednesday, 6/15/2016
Doors at 7pm, Show at 8pm
Rickshaw Stop, 155 Fell St @Van Ness
$8, all ages
Tickets here

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“Mudlarking and Material Culture” by Laura Rubin

The River Thames has a long memory. The river and its tributaries have shaped and informed the daily life of Londoners from lithic times all the way to the present, and preserve the material culture of their daily lives. In this lecture Laura Rubin will give a brief overview of the Thames, a short methodology, and talk about her personal finds from the summer of 2015.

Laura is a costumer, writer, and interdisciplinary scholar. When not writing software manuals for money, she researches and interprets Western clothing, foodways, and culture from the 16th through the 20th centuries.

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“The Blind Watchmaker: Theo Jansen and the Art of Creating Life” by Paul Dancstep

“Strandbeest: The Dream Machines of Theo Jansen” is a new exhibit at the Exploratorium. It features the work of a Dutch artist who creates elaborate walking structures out of PVC tube. These “strandbeests” are made up of many interesting organs. They have legs that take elegant strides. They have stomachs to store energy, allowing them to walk even when there’s no wind. They can even detect water and count their steps. Explore strandbeest anatomy and what it reveals about living creatures and the process of natural selection.

Paul grew up in San Diego but has never been on a surfboard. He studied physics in college but is still baffled by things like zippers. He’s been at the Exploratorium for over a decade, building boxes, changing lightbulbs and occasionally speaking to the public.

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“Mite-y Sexy: The Scandalous Sex Lives of Mites” by Jane Ishka

There are more species of mites than anything else on earth, and almost as many weird ways that they have sex. Some male mites carry immature females until they grown up and are ready to mate, while certain females mate once and carry the sperm for their whole lives, impregnating themselves at any time. Hear these and more Barely Safe For Nerd Nite sex stories about the mighty mite!

Jane is the author of The Year of the Mite and a biotechnology professional living in Berkeley. Her technical writing supports approval of new medical products. Her first book, The Year of the Mite, chronicles a year-long infestation of her home and skin by the parasite Dermanyssus gallinae. Visit Jane at www.yearofthemite.com

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With: Alpha Bravo, who’ll be spinning tunes specially selected to match the presenters’ themes. Follow the setlist on Twitter @djalphabravo.

Plus: The San Francisco Public Library will be on hand to dole out library cards, reading lists, and the hottest branch gossip.

Nerd Nite SF #72: Submarines, DNA Nanotech, and Affordable SF Housing!

Nerd Nite SF #72: Submarines, DNA Nanotech, and Affordable SF Housing!Wednesday, 5/18/2016
Doors at 7pm, Show at 8pm
Rickshaw Stop, 155 Fell St @Van Ness
$8, all ages
Tickets here

This month we’re dealing in the UNBELIEVABLE: wonderful weirdos of the ocean, nano-building blocks of DNA, and–the farthest of the fetched–affordable housing in San Francisco. So, take a deep breath and a big sip of your drink as our expert presenters, bartenders, deejay, librarians, and the Grilled Cheese Guy help us come to terms with it all. But only if you do this in the first place: Be there and be square!

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“Submarine in the Abyss: Exploring the Ocean from a Tiny Metal Tube” by Erika Bergman

We hope you are wearing clean socks, because you are about to kick off your boat shoes and climb into a deep-sea submersible! Explore an underwater world dominated by giant tube worms, heat-tolerant shrimpies, vast bioluminescent networks, shipwrecks, and…beer bottles? The ocean makes up 90% of the living space on the planet, and we’re not the only weirdos down there.

Erika is a mechanic, tech enthusiast, and explorer for National Geographic. She founded theGEECs.com, whose first program is Girls Underwater Robot Camps, and hopes to hire all the little girls who don’t yet realize they are destined to be engineers and explorers.

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“Tiny Tools: A 40-year Quest to Build with DNA” by Shawn Douglas

Nearly four decades ago, a young scientist named Ned Seeman had a Eureka moment. He realized that DNA molecules might be repurposed as nano-sized “Lego” blocks in order to build tools to solve one of the most fundamental challenges in molecular biology: determining atomic structures of proteins. Ned went on to pioneer an entirely new area of research: DNA nanotechnology. I’ll share an update from the field, including how we may be tantalizingly close to realizing Ned’s vision, albeit with a new spin on his original approach.

Shawn Douglas earned a B.S. in Computer Science at Yale in 2003, and then a Ph.D. in Biophysics at Harvard in 2009, working in the laboratories of William Shih and George Church. He continued at Harvard as a Postdoctoral Fellow at the Wyss Institute for Biologically Inspired Engineering, and recently started his own lab as an Assistant Professor at UCSF. He was named as one of Popular Science magazine’s “Brilliant 10” in 2012, and has presented for Google Solve for X and Bloomberg BusinessWeek Design conferences.

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“Hidden Histories of Affordability in San Francisco” by Michael Epstein

Remember when a housing upgrade was as simple as physically moving your house from one part of San Francisco to another? Or when you could just plop a house on a barge and pay a modest slip fee? Or when foraging tribes would spend their winters in the hills and summers by the Bay creating huge shell mounds from the remainders of seafood feasts? Affordable living has a rich history in San Francisco, and, if you know where to look, some vestiges still remain. This presentation will reveal several hidden landmarks of SF affordable housing and speculate on how they may inform current efforts to keep the city economically diverse.

Michael teaches location-based media courses at the California College of Art and produces apps for urban exploration with Walking Cinema.

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With: Alpha Bravo, who’ll be spinning tunes specially selected to match the presenters’ themes. Follow the setlist on Twitter @djalphabravo.

Food: Delicious hot goop between crispy slices of bread, brought to you by the scientist of the sammie, Grilled Cheese Guy.

Plus: The San Francisco Public Library will be on hand to dole out library cards, reading lists, and the hottest branch gossip.

Nerd Nite SF #71: DNA Day, Butterfly Genomics, Baseball Analytics, & Tobacco Control

Nerd Nite SF #71: DNA Day, Butterfly Genomics, Baseball Analytics, & Tobacco ControlWednesday, 4/20/2016
Doors at 7, show at 8
Rickshaw Stop, 155 Fell Street @Van Ness
$8, all ages
Tickets here

Toast to the double helix with the most at this month’s Nerd Nite SF! But that’s not all – we’ll learn what baseball analytics has to teach us about data science, and how vaping is changing the tobacco control game. Plus there’ll be science rhymes, bao, librarians, libations, and a whole lotta smart people in the audience. Get your start codon together, because it’s on!

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National DNA Day
DNA Day commemorates the completion of the Human Genome Project and the publication of DNA’s double helix structure in Aprils 2003 and 1953, respectively. We’re doing our part in a very Nerd Nite way with Tom McFadden kicking the night off with a science history rap battle of Rosalind Franklin vs Watson & Crick, and serving up DNAquiries – a strawberry + rum shot where the strawberry DNA precipitates out and forms a nice viscous layer in the drink. Yum!

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Guest MC: Tom McFadden
Tom is the host of “Science with Tom”, and he’ll be your MC for the evening. Tom works with middle school students to research, write, and perform their own science raps, and he has been known to spit hot lyrical fire of his own. Tom started science rapping in 7th grade, then at Stanford, then with kids around the world. He got a Masters in Science Rapping on a Fulbright Scholarship in New Zealand. He’s now teaching 8th-grade science at The Nueva School in Hillsborough.

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“The Science, Joy, and Heartache of Baseball Analytics” by Tracy Altman, PhD.

A beautiful thing about data science is that so-called outsiders can contribute meaningfully. Baseball analytics is a perfect example: An early version of citizen scientists recorded MLB play-by-plays for geeks everywhere – triggering lawsuits and fueling tech companies. Tracy will show how sports analytics parallel most applications of data science. ‘Inside baseball’ is a great place for anyone who wants to understand how data helps people make better decisions.

Tracy Altman, PhD, is the founder of Ugly Research in Oakland. She has wrangled data and created analytical content for decision makers in oil and gas investing, science publishing, pharmaceutical R&D, and baseball statistics.

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“Hot Aerosol: E-Cigs, Tobacco Control, and the Nicotine Endgame” by C.A.B. Fredericks

Cigarettes are SPECTACULARLY bad for you. There are few things you can do to reduce your chances of dying awfully more than quitting. E-cigarettes are Not Cigarettes, and this has generated lots of enthusiasm, confusion, and very decisive statements in the face of vast voids of knowledge. This presentation explores three big debates about e-cigs/vapes: do they help you quit, are they harm reduction, and what does nicotine addiction really mean?

C.A.B. Fredericks is a former smoker who now works for the UCSF Center for Tobacco Control Research and Education. His interests include addiction research, behavioral health in vulnerable populations, and fantasy baseball, which he probably should’ve lectured on instead.

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With: Alpha Bravo, who’ll be spinning tunes specially selected to match the presenters’ themes. Follow the setlist on Twitter @djalphabravo.

Food: Delicious pork belly bao and other bun-goodness from CrossHatch Eatery.

Plus: The San Francisco Public Library will be on hand to dole out library cards, reading lists, and the hottest branch gossip.